The only FDA-Approved treatment for Lysosomal Acid Lipase Deficiency (LAL-D)

KANUMA® (sebelipase alfa) is a prescription medication used to treat people with a diagnosis of LAL-D.

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Kanuma® (sebelipase alfa) is administered via infusion

KANUMA is indicated for the treatment of people with a diagnosis of LAL-D and is administered as an infusion by a healthcare professional.

For more information on KANUMA infusions:

Download Infusion Brochure

Getting Started on Kanuma

KANUMA is indicated for the treatment of patients with a diagnosis of LAL-D. Once your doctor has determined that KANUMA is right for you, sign up for OneSource™, and personalized patient support program from Alexion Pharmaceuticals.

There are 2 ways to get access to OneSource:

Call 1-888-765-4747

Get in touch with a OneSource nurse case manager.

Download the OneSource enrollment form below

Print this form, sign it, and submit it to OneSource. Someone will be in touch within the next business day.

Submit via email:

Submit via fax: 1-781-240-8003

Download OneSource enrollment form

KANUMA support by OneSource

Once your doctor has decided that KANUMA is right for you, OneSource is here to help. Alexion’s objective is that every person living with LAL-D who can benefit from KANUMA will have access to it. After signing up, you will be matched with a dedicated Alexion nurse case manager who can help answer any questions you may have about KANUMA or LAL-D.

OneSource is staffed by Alexion nurse case managers who provide one-to-one education, information on funding options and access to KANUMA, and ongoing treatment support for people living with LAL-D, and their caregivers.

Our Nurse Case Managers provide personalized support:

  • Assistance from a dedicated nurse case manager
  • Answers to questions about LAL-D or KANUMA
  • Resources and education on the infusion process
  • Help connecting patients with other families affected by LAL-D

Financial assistance programs can help with out-of-pocket expenses for KANUMA:

  • The Alexion Commercial Co-pay Program can limit out-of-pocket expenses to $5 for eligible patients with commercial insurance
  • OneSource can also provide referrals to independent foundations for patients without commercial insurance and for other treatment-related costs
  • OneSource nurse case managers are reimbursement experts that can also help navigate the insurance approval process for benefits investigation and coverage, including prior authorizations

Get connected with your

OneSource nurse

case manager


Monday through Friday,

8:30 AM to 5 PM (ET)